Recombinant Human NPDC-1/NPDC1 Protein (His Tag)

Recombinant Human NPDC-1/NPDC1 Protein (His Tag)

SKU #	PKSH032822
Expression Host	HEK293 Cells

Description

Synonyms	CAB,CAB-1,CAB1,NPDC-1,NPDC1,Neural Proliferation Differentiation and Control Protein 1,RP11-229P13.1
Species	Human
Expression Host	HEK293 Cells
Sequence	Gly35-Asp181
Accession	Q9NQX5
Calculated Molecular Weight	16.5 kDa
Observed Molecular Weight	28-35 kDa
Tag	C-His
Bio-activity	Not validated for activity

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin	< 1.0 EU per g of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80. Reconstituted protein solution can be stored at 4-8 for 2-7 days. Aliquots of reconstituted samples are stable at < -20 for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 m filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background
Neural proliferation differentiation and control protein 1(NPDC1) is a protein that in humans is encoded by the NPDC1 gene. It is a single-pass membrane protein and belongs to the NPDC1/cab-1 family. The protein strongly expressed in adult brain and especially in hippocampus; frontal lobe and temporal lobe. The protein suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation and it might be involved in transcriptional regulation.